"Earth's strongest female on a path of destruction! Red She-Hulk finds herself outnumbered and outgunned when she wages a war against the world's super-humans, and her first target - a new U.S. military super-soldier program - draws the attention of Captain America and Machine Man! As Cap joins the fray, the Avengers are never far behind, and Red She-Hulk takes on all comers - battling Earth's Mightiest Heroes in a jaw-dropping, aerial slugfest. Meanwhile, Machine Man tumbles down the rabbit hole as he investigates what Red She-Hulk's alter-ego Betty Ross may know about the future and human extinction, and how it brought her into conflict with the Avengers!" -- P.  of cover.